Next to Gamal Abdel Nasser (Or Nasser) metro station, get away from the busy streets and find yourself a terrace seat. They regularly play nice music, food, Shisha, and beer are not bad with very reasonable prices. The place is inside Carlton Hotel, please note that you might have to leave your luggage at the reception to enter.
A nice cafe to end a trip through downtown with. Very close to transportation. You can choose either indoor or outdoor seats. Usually not crowded and staff are quite nice. The hotel itself is very vintage with artistic looks. Give it a try :)
Might have to leave luggage at the entrance (for safety issues), make sure you don't forget them on the way out.