Caffe Milani has a great location that is next to the Wenceslas square and less than 5 minutes far from the Old Town Square too. My friends and I would often come here to study for a couple of hours, or just have a quick tasty meal.
Easily accessible with good prices! My absolute favorite is their takeaway latte, which comes in a big cup and tastes absolutely amazing. So even if you don't have much time, you can pop in quickly and grab a cup for your wandering around Prague.
Su-Sa: 08:00-23:00