Blind Lady Ale House (known as BLAH to locals) always has great local brews on tap, and often has special beer tastings and events. Their pizzas are creative and not your usual greasy pepperoni options. Get an egg, fresh local cheese, and locally sourced meats on your pizza.
You won't find tourists here. There are other great bars in the Normal Heights neighborhood, so it's a great start for a longer night out. It's a grown up place (no drunk 21 year olds) but also kid friendly, which is great for the local aging hipster scene.
If you really, really love beer, bring your growler, as you can fill it up for specially chosen beers to take home.