On Thursday nights the Academy of Science brings in a DJ and serves cocktails (age +21) as you walk around exhibits. Each week is a different theme so be sure to check out http://www.calacademy.org/nightlife and pick your favorite.
It's a fun spin on going to a museum.
Look for Claude, the albino alligator who lives at the Academy of Science.
Mon-Sa: 09:30-17:00
Su: 11:00-17:00