Ike's place serves delicious sandwiches of huge proportion made with crunchy bread and tasty secret sauce (the "dirty sauce"), for a price that is not so expensive (for San Francisco). Locals generally line up during lunch time to get their favorite sandwiches in Castro.
The variety of bread, meat and vegan option offered is endless. Every sandwich gets its own particular name, and it is fun to discover their different taste. The vegetarian sandwiches are especially good, I recommend the "Sometimes I'm a Vegetarian" or "Stupid Eggplant". And for meat lover, the "Ménage à trois" is a classic (and fatty) one.
Make your wait worthwile (expect 30-40mn during rush hours) by reading all the great and fun names of the sandwiches in the menu.